Dr. Jimmy Kildare and Nurse Mary Lamont are all sent to get married and her brother Doug Lamont has come to New York. When Jimmy meets him he notices strange behavior on his part such as sudden inattention or acting as if he was hearing sounds that are non-existent. The doctor starts to diagnose him and comes to the conclusion that he probably has epilepsy, a hereditary disease that could conceivably affect Mary as well, even though she has never shown any symptoms. Dr. Kildare is worried about this part of medicine and how you tell someone that they have a disease that they can do nothing about. It's left to Dr. Leonard Gillespie to come up with a solution and ensure that Jimmy and Mary can still get married.
Dr. James Kildare has just completed his internship at Blair General Hospital and is assigned to work with his mentor, Dr. Leonard Gillespie. But fearing for the health of his father, Dr. Stephen Kildare, he returns to his parents home in Parkersville to help him with his excessive workload servicing a wide area ever since other doctors moved elsewhere. Noting that three doctors at Blair General are doing menial jobs because they can't start practice, Kildare conceives the idea of building a clinic in Parkersville to be serviced by the three doctors and financed by the townsfolk paying ten cents a week to subscribe to the service. But influential men in Parkersville provide serious opposition to the plan.
Fresh out of medical school, young Dr. James Kildare decides to leave his father's country practice and take up a position at a large New York hospital. There he meets the famous Dr. Leonard Gillespie who becomes his mentor. Kildare finds himself in serious trouble when he saves a suicidal woman who turns out to be an heiress with a powerful family.
Something scary is happening to boys today. From kindergarten to college, they are less resilient and less ambitious than they were a mere 20 years ago. Fully one-third of men ages 22 to 34 are still living at home with their parents, about a 100 percent increase in the past 20 years. Boys nationwide are increasingly dropping out of school; fewer are going to college.